TECH EXPERT
Dr Gu Keyu

Dr Gu Keyu

Lecturer

Republic Polytechnic

EXPERTISE:
Life Sciences - Product Design & Development, Prototype Build
LOCATION:
Singapore

BIOGRAPHY

Dr Gu Keyu has a BA in Agronomy and PhD in Plant Genetics and Breeding from Nanjing Agricultural University of China. Prior to joining Republic Polytechnic, he has various positions at the Institute of Molecular Agrobiotechnology (IMA) and Temasek Life Sciences Laboratory (TLL), National University of Singapore. As a senior Post-doctoral Fellow, he published about 20 papers as first authors or co-authors in journals such as Theoretical and Applied Genetics, Plant Cell Report, Nature, Molecular Plant Pathology, BMC Research Notes, Plant Science, PLOS ONE, Plant Cell, Biotechnology for Biofuel, BMC Plant Biology, MPMI etc. 

His current research interests are in vegetable growth promotion and heat/drought stress tolerance, substrate-based hydroponics production, plant disease resistance, and hydroponic plant nutrient recipe formulations etc.

PORTFOLIO

Rice Bacterial Blight Disease Resistance Gene Cloning

As an important food in Asia, rice has three major diseases including bacterial blight, blast and sheath blight. To increase the rice bacterial blight disease resistance, Dr Gu and his team cloned two important disease resistance genes (R-genes), Xa27 and Xa10. Xa27 shows resistance to 30 strains out of 35 collected strains worldwide. However, Xa10 confers race-specific resistance which only contributes resistance to strains harboring avrXa10. He was mainly involved in genetic and physical mapping, transgenic fragment analysis, plant inoculation, gene expression, yeast one-hybrid analysis, etc. 


Expertise Provided
  • Life Sciences - Product Design & Development
Development of Insect Resistant and Toxin-free Jatropha Seeds

To reduce global warming, plant scientists are trying to develop biofuel to partially replace chemical oil. As a non-food biofuel plant, jatropha curcas’ seed contain about 40% high quality oil. Based on this, Dr Gu was involved in transforming the Bt (Bacillus thuringiensis) gene into Jatropha and obtained single copy marker-free transgenic Jatropha, which showed insect resistance. However, even though Jatropha shows strong drought tolerant, its leaf and seeds contain some toxins such as curcin. To knock down the curcin gene in Jatropha seeds, they used endosperm-specific RNAi gene-silencing to knock down curcin expression in seeds and produced curcin-deficient jatropha. 
 


Expertise Provided
  • Life Sciences - Product Design & Development
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