TECH OFFER

Equol Formulation for Skin and Hair Cosmetics Applications

KEY INFORMATION

TECHNOLOGY CATEGORY:
Personal Care - Cosmetics & Hair
TECHNOLOGY READINESS LEVEL (TRL):
LOCATION:
United States
ID NUMBER:
TO146543

TECHNOLOGY OVERVIEW

Many botanical extracts, such as polyphenols and keto-carotenoid, are commonly used in cosmetics for their anti-oxidant, growth factor, skin lightening, extracellular matrix support, UV-protective and anti-inflammatory or anti-ageing properties. 

An American University has discovered that Equol, an isoflavonoid molecule, has many skin anti-aging properties. Positive effects on the skin include reduced inflammation and ageing genes, a reduction of fine and medium lines and wrinkles, as well as a more youthful appearance of skin. For hair, Equol has shown promise in treating baldness by retaining and growing hair. This botanical active has been registered with the Personal Care Products Council (PCPC) for over 9 years and is known for uses in topical cosmetics and oral supplements. 

The proprietary Equol technology, consisting of topical and oral, cosmetic and hair formulations, is protected by patents for topical and oral cosmetic applications. 

TECHNOLOGY FEATURES & SPECIFICATIONS

Equol works as an anti-ageing molecule by guarding against oxidative stress and decreasing Reactive Oxygen Species (ROS).

Protects against oxidative stress:

  • Inhibits AP-1 and Neoplastic Cell Growtih via ERR-y
  • Protects DNA and enhances nerve/tissue repair
  • Binds 5α-DHT and ERß in skin and scalp tissues for photo-protection
  • Stimulates collagen, elastin and TIMP 1
  • Inhibits MMPs, Elastase and 5α-Reductase Enzyme

Decreases Reactive Oxygen Species (ROS):

  • Inhibits NFkappB
  • Inhibits inflammatory response
  • Stimulates Nrf2 to increase antioxidants

POTENTIAL APPLICATIONS

The technology is an anchor active ingredient for several types of skin and hair care products in a sustainable, natural product line promoting both topical and ingestible applications.

There following formulas of Equol are available for incorporation into a cosmetic or personal care line:

  • Moisturising serum
  • Night complex
  • Foaming cleanser
  • Hair formula for scalp hair retention
  • Enhancement for male and female pattern baldness

Benefits

Equol is able to provide the following customer benefits:

  • Enhance dermal collagen and elastin
  • Inhibit matrix metalloproteinases (MMPs) that breakdown dermal collagen and elastin
  • Decrease negative androgenic hormonal influences in the skin
  • Enhance estrogenic hormonal influences in the skin without the negative perception of estrogen on health
  • Decrease the appearance of fine and medium lines and wrinkles
  • Enhance skin integrity/repair/health by decreasing oxidative stress to counteract chronological and photoageing
  • Enhance and elevate a woman's appearance so that they can feel better about themselves
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