Bioactive Novel Milk Protein Extract for Immunity and Digestive Health


Personal Care - Cosmetics & Hair
Personal Care - Nutrition & Health Supplements
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New Zealand


A New Zealand company has patented a novel milk fraction which has active and proven antimicrobial, antioxidant and anti-inflammatory properties. Extracted from some of the highest quality milk in the world, these natural immune defense proteins provide a powerful defensive shield against infection and support the body’s innate immune system. 


Compared to other milk proteins, this proprietary broad-spectrum ingredient exhibits superior anti-bacterial inhibitory power against four common pathogens: Escherichia coli, Staphylococcus aureus, Cronobacter sakazakii and Klebsiella aerogenes compared with other bioactive proteins. It also provides effective microbiome supportdue to its selective antimicrobial activity – while it is a very effective inhibitor of many pathogens, it is far less effective in inhibiting commensal and probiotic species which are important for digestive and immune health.  The immune defense proteins also provide effective anti-inflammatory inhibition. This was determined by measuring its ability to inhibit the inflammatory markers interleukin-6 IL-6 and tumor necrosis factor TNF- α-. The results for the immune defense proteins were comparable to Aspirin at the same concentration. In terms of antioxidant activity, the novel milk protein reports an ORAC value within the top 10 dried antioxidant fruits, vegetables and spices such as wild blueberry, elderberry and goji berry. Furthermore, the ingredient has been shown to work well with glucosamine and chondroitin in providing a more effective anti-inflammatory complex.

The ingredient is a naturally derived component of milk and its major constituents, lactoferrin and lactoperoxidase along with over 50 other milk defense proteins are all GRAS in various applications. In addition, the company employs a specialised extraction process which excludes potentially allergenic proteins and it does not contain lactose. Studies carried out demonstrate ingestion safety and no adverse effects for topical use.


The novel ingredient is a natural and effective solution to boost immunity and digestive health, as well as promote healthy ageing by providing natural protection from free radicals, inflammation and infection. As a potent inhibitor of harmful pathogens, along with its soothing anti-inflammatory and healing antioxidant effects, the milk protein can be particularly helpful for:

  • Digestive health and immune support
  • Skin conditions caused by Candida and Malassexia such as eczema and psoriasis that are the result of an excessive inflammatory response to infection
  • Skin and wound infections caused by bacteria such as Staphylococci and Streptococci
  • Acne, which is caused by the growth of Propionibacterium acnes in hair follicles, with the recruitment of white blood cells resulting in pimples
  • Dental hygiene issues such as bad breath, irritated throats and decreased gum health
  • Daily exposure to the skin from sun, wind, chemicals, bacteria, and pollution produce inflammation and oxidative stress that overwhelms the antioxidant capacity of the skin

The ingredient has been successfully used in a number of applications including:

  • Milk protein powder nutritional supplements (3yrs +)
  • Flaxseed oil nutritional supplements
  • Topical cream and spot gelfor preventing the spread of acne and reducing redness/irritation

Other applications include but is not limited to:

  • Food
  • Supplements
  • Personal Care
  • Cosmetics
  • Animal health remedies


The ingredient meets the growing consumer demand for safe, natural and effective solutions to boost immunity and digestive health. Benefits of the proprietary milk protein include:

  • Stronger immune function
  • Better gut microbiome and digestive health
  • Antioxidant, anti-inflammatory and antibacterial activity
  • Safe and natural solution extracted from high-quality fresh milk
  • Healthy ageing 

The New Zealand company's expertise in research will provide the basis for the successful development and commercialisation of natural health products based on this novel milk protein.

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