This Spanish organisation leverages on Industrial Biotechnology or “White Biotechnology” techniques using microorganisms and enzymes, to obtain products of industrial interest for different sectors such as chemical, agricultural, food, feed, cosmetics and pharma.
The industrial biotech platform offered here helps to develop and optimise processes for the highest economic feasibility.
The industrial biotechnology includes three main areas:
The process development is divided in four main stages:
1. MICROORGANISM: The starting point can be a microorganism from the in-house collection, a natural isolate or a genetic engineered strain. A functionality screening (in vitro) is performed at this point to check if the microorganism/cell is producing the desired effect or molecule.
2. BIOPROCESS (UPSTREAM): To find the optimum operating conditions to ensure an industrial process with maximum viability, intensive and extensive variables are optimized using statistical experimental design, at our lab with different reactor scales (bench, 1L, 5L, 20L, 200L).
3. DOWNSTREAM: depending on the molecule and the target purity, different physical separation (centrifugation, tangential filtration) and purification methods are applied.
4. STABILIZATION: The compound is stabilized with the appropriate method (lyophilisation, spray-drying, microencapsulation, etc) depending on the requirements of the final product.
Examples of products that can be developed:
Customers can benefit from the organisation’s deep experience in the end-to-end development of bioprocesses. It is also possible to obtain significant samples for evaluation or even batches production.