TECH OFFER

Plant-Derived Nano-delivery Technology to Improve Bioavailability of Actives

KEY INFORMATION

TECHNOLOGY CATEGORY:
Healthcare - Pharmaceuticals & Therapeutics
TECHNOLOGY READINESS LEVEL (TRL):
LOCATION:
Canada
ID NUMBER:
TO162673

TECHNOLOGY OVERVIEW

This technology offer is plant-derived nanoparticles that act as carriers of large numbers of biologically active payloads into living cells of plants, animals and humans. The nanoparticles protect the actives from degradation and transport them into the cytoplasm. Data indicates that the internalization process is not endocytotic in nature. The nanodelivery system is being deployed in several applications including food, beverage, agriculture and pharmaceuticals.

TECHNOLOGY FEATURES & SPECIFICATIONS

There are two different nanostructures made from the same plant materials. They have different biophysical properties and thus are used in different applications. The technology is patented covering composition, manufacturing process and uses. Results from three animal studies are available showing efficacy in a nutrition supplement model. There is also in-vitro data in models of cancer showing profound efficacy in MDR (multiple drug resistant) cancers.

POTENTIAL APPLICATIONS

  • Agriculture
  • Optimizing RNAi delivery, pest control
  • Post harvest technology – increased shelf life
  • Phytosanitary antipathogen agents
  •  Human Health, Wellness & Nutrition
  • SlimLiiv™ – obesity control, anti-inflammatory
  • Topicals for inflammation of joints
  • Increase bioavailability of pharmaceuticals
  • Food & Beverage
  • Stabilize water-insoluble beverage components
  • Drinks to control chronic pain
  • Nutrition bars
  • Animal Nutrition & Health
  • Increase bioavailability vitamins/metals
  • Increase bioavailability of pharmaceuticals

Market Trends & Opportunities

The markets for this technology are large and growing globally. We summarize them as follows:

Market                      Size (US$B)            Growth Rate (%)                            

Weight Loss Supplement   $23                      6.0

Food Ingredient                $34                     7.8

Agricultural Biotech           $89                     7.1

Pharma - Cancer              $121                    7.4

Pharma - Inf Diseases      $42                      3.0

Cannabis Legal                 $50                    40.0

Benefits

Our technology overcomes the problem of poor bioavailability. We can deliver bioligically active molecules orally in high concentrations. This can:

  • improve efficacy
  • speed onset of action
  • avoid degradation
  • lower cost of goods
  • improve the environment due lower of greenhouse gas emmissions

Our material is anti-inflammatory as opposed to the state of the art lipid based nanomaterials which are pro-inflammatory.

RELATED TECH OFFERS
Therapeutic Inhibitor for Epstein-Barr Virus (EBV)-associated Cancers
Cancer Catcher - Early Detection of Circulating Tumour Cells
Potent Anti-bacterial Plant Oil for Skin Health and Ailment
Melanin Derived From Black Soldier Flies
Non-Invasive, Non-Toxic Encapsulation Technology to Prolong Effects of Leave-on Products
Novel Anti-microbial Agent for Preventing Dental Caries
Growth Factor-free Proliferation & Differentiation of Stem Cell
A modified Chinese Medicine formulation for treating Alzheimer's disease
Plant-Harvested Biopolymer for Postsurgical Adhesion Barrier Gel and Film Application
Nano-vesicles for Improving Drug’s Stability and Efficacy to Treat Chronic Diseases