The technology offers an effective and hygienic solution for capturing first void urine (typically defined as the first 20 mL of the urine flow) in a standardized volumetric way, thereby guaranteeing significantly increased analytic accuracy and patient comfort over classic urine sampling devices. The technology is highly user-friendly and allows for non-clinician dependent self-sampling in a home based setting.
Due to the non-invasive character of urine sampling, it offers an alternative to clinician-dependent sampling such as pap smear, cervico-vaginal brushes, etc.
The technology platform consists of multiple variants capturing a range of urine volumes for different application purposes. To allow for transportation and storage of the urine sample at room temperature, the technology is also available in combination with various urine stabilization chemistries that remove the need for cold-chain transportation and immediate cold storage of the collected samples.
The device is comprised of a housing component and a urine sampling tube. The design of the device allows a continuous urine flow and a fully hygienic sample taking and is decisively more user-friendly than a classic urine cup.
For each of the volume variants, the sampling tube is available in a neat fashion, but also prefilled with various urine stabilization chemistries. These stabilization buffers allow for transportation and storage of the urine sample at room temperature, and for an effective preservation of the urine samples, and thereby of the urine analytes of interest (nucleic acids, extracellular vesicles, proteins, cells, bacteria, etc).
Several trends are seen in both the infectious diseases and oncology markets:
The technology is offering the possibility for home-based urine collection, in a way that is compatible with various applications, and also directly compatible with automated high throughput lab systems. By reducing the overall turn-around time from sampling to result, use of personalized medicine can be favoured over the use of generic medicine.
Furthermore, small volume variants of the technology are designed in such a way that the urine collection tube is compatible with various automated, high throughput analysis systems. This removes the need for unnecessary manual sample preparation and handling, and thereby (1) lowers the total cost of the sample analysis, (2) lowers the error rate, generally attributed to manual sample preparation steps, and (3) lowers the overall lead time from sample-to-result.