TECH OFFER

Silk Fibroin Membrane as Artificial Stratum Corneum for Cosmetics Industry

KEY INFORMATION

TECHNOLOGY CATEGORY:
- Healthcare
TECHNOLOGY READINESS LEVEL (TRL):
LOCATION:
Singapore
ID NUMBER:
TO174228

TECHNOLOGY OVERVIEW

The market of personal care products is highly fragmented and competitive. Product development and innovation are key measures to gain competitive edge in the market. Performing tests on these products are essential in product development for product evaluation and regulatory purposes. However, animal study is currently widely banned, panel test has the drawback of wide personal bias, and current commercial skin mimics are expensive yet their performance is still far from real skin. Fabricated from a natural protein, silk artificial stratum corneum (SC) have similar keratin structure with real skin stratum corneum, the key component for skin barrier. Compared with other artificial-skin testing platform, silk artificial SC is more relevant to real skin in terms of skin-related products testing results and can also be customized for various skin types (dry/oily/combined). We are seeking for collaborations on manufacturing and products testing. Chemicals and consumers good company can be the customer for licensing the technology.

TECHNOLOGY FEATURES & SPECIFICATIONS

Feature & Advantages Use natural protein silk with similar composition with keratin, key component of skin barrier. Compared to commercially available products, silk artificial SC can recreate the interaction of personal care products with skin by tuning the surface property, topology, pH and absorption behavior similar with real skin. Silk artificial SC can be customized for dry, normal and oily facial skin. Fabrication process is all water-base, green process. Silk artificial SC is fairly cost-efficient compared to its commercially available products Provide an economical solution for quantitative personal care products tests with high consistency and reliability. Specifications Raw materials: regenerated silk processed from silk fibers extracted from silkworms, PEG derivatives (poly(ethylene glycol) diglycidyl ether and poly(ethylene glycol) diacrylate). Finished product can be tuned to different shape and thickness according to different needs.

POTENTIAL APPLICATIONS

Since 2013, as ethics for animal experiments has been strengthened in the European Union, artificial skin models have attracted attention as an alternative to animal testing for assessing the effectiveness, safety and toxicity of Skicare products. The developed silk fibroin membrane as artificial stratum corneum for cosmetics industry is able to provide realiable testing data at low cost for the development of skincare products. The potential applications are: Testing kit for personal care product development (skincare products, cosmetics, perfume etc.). Testing service for companies without their own in-house testing platform

Benefits

Speed products iteration/innovation to meet consumers’ changing need. Quantitative and convenient screening/measurement of product performance Large testing capacity, time –efficient, cost efficient Reduce/eliminate animals tests Cost-saving on sourcing customer study
RELATED TECH OFFERS
Painless Dissolvable Microneedle Patches for Cosmetic and Biomedical Applications
Eye Drop Guide Device for Instilling Eye Drops
Never Ever Fall (NEF) On-Bed Monitoring and Notification System
MRBA (Mobile Robotic Balance Assistance)
Locally-flavoured Pre-Thickened Beverages For Patients With Swallowing Difficulties