With the increasing global ban of animal testing in this era, particularly for cosmetic-related products, research and development is greatly hindered. In addition, many of today's animal and cell-based toxicity testing models are burdened by significant accuracy, reproducibility, cost and ethical concerns. Adoption of In-vitro models have increased, due to the resemblance to the human skin, it is paced to fulfill efficacy claims ethically & build brand image. However, current OTCs (organotypic co-cultures) fail to represent the various skin conditions, such as wrinkled ageing skin, dry skin, haired skin and immunogenic skin. Few existing services address the demand of the dermatological-related companies for claim validation of products on different types of in vitro skin substitutes that model the various human skin conditions. This technology provides for an asian 3D organoid in-vitroskin model for translational research and testing.
This technology has the following features: Asian skin origin 3D human skin model cultured in Chemically Defined Serum-Free Environment Proper Stratification For Functional Skin Barrier Fully Human Origin Cell Lines/ Primary Cells Choice Of Topical Or Systemic Application Choice of Ex-vivoskin included Flexible Platform That Incorporates More Than 2 Cell Types Alternatives to animal testing
This technology can be used as a platform for dermatological products validation or further testing or development. Other applications of this technology include: Product development (e.g. dermatological product development and testing) Product Validation Platform Skin Microbial Ecosystem Studies Product Efficacy & Response Assessment Research Studies requiring use of 3D human skin model In-Vitro Wound Healing Studies
Improvedbrand image Significant accuracy in human 3D model Enhanced reproducibilityof test results Negotiable cost Address ethical concerns