Improved Carboxymethyl Cellulose (CMC) Foam for Hemostatic and Wound Healing

Technology Overview

The technology offered is an improved version of carboxymethyl cellulose (CMC) foam and the method of producing it. The CMC foam produced by this company features several outstanding characteristics that make it ideal as a hemostatic and wound healing agent. Highly water insoluble, this CMC foam provides an effective protection barrier in wound dressings. It also features an excellent capability in the absorption of liquids including body fluids, blood exudates and moisture. Furthermore, while this CMC foam boasts a higher volume expansion above that currently offered in the market, it does not like other CMC foams, gelate even after liquid absorption. This remarkable quality enables the foam to retain its shape even after expansion, hence demonstrating markedly improved hemostatic and wound healing functions. 

Technology Features & Specifications

Highly biocompatible, CMC is used in various industries from food to cosmetics. In the medical industry, CMC foam is widely used in products such as adhesion barriers, wound healing agents, hemostatic agents and more.  However, the CMC foams developed so far for these purposes have a poor expansibility of 150% or less. The foams also gelate after absorbing liquid, thus causing them to lose their shape. Through the 4-step process outlined below, the company has produced an improved CMC foam to facilitate faster wound healing:

  • Step 1: CMC powder is freeze dried as foam
  • Step 2: Foam is immersed in an acid solution at 40°C to 70°C
  • Step 3: Foam is further immersed in a dispersion containing a CMC solution
  • Step 4: Foam is compressed at 60°C or below

The dispersion process in Step 3 changes the surface characteristics of the CMC foam to prevent adhesion to the skin. It also allows further control of the foam’s degree of liquid absorption, which thus may be customised depending on the intended purpose.

Potential Applications

This CMC foam is designed to improve the effectiveness of medical dressing consumables such as hemostats and wound dressings. Due to its biocompatibility, it may find further application in cosmetics, glues, oil drilling, pharmaceutical drugs and food as an additive or thickening agent.

Market Trends and Opportunities

The global wound dressing market is expected to grow from USD 6.31 billion (2016) to USD 8.46 billion by 2021 with a CAGR of 6.4% during the forecast period. Wound infection, and its prevention, continues to be major health concern among patients and healthcare professionals globally. With the expected rise in diabetic patients due to a greater ageing population, the market is expected to grow as the demand for wound care management to treat both acute and chronic wounds such as diabetic foot ulcers and foot cuts increases. 

Customer Benefits

With the following characteristics, this technology effectively deals with the challenges in effective wound care such as leakage, maceration and infection, creating an optimal healing environment to facilitate better wound care management. It enhances patient well-being and quality of life while improving treatment outcomes for the healthcare industry:

  • High water solubility
  • High liquid absorption rate, with ability to be customised
  • Higher volume expansion rate than current market offer
  • Retains shape without gelation

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