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Non-Occluding Continuous Blood Pressure Measurement Method targeted at rapid triage management

Technology Overview

Blood Pressure (BP) measurement is a vital clinical parameter in healthcare. One challenge in today’s increasingly complex healthcare environment is the need to obtain BP measurements continuously from subjects during daily activities including exercise and sleep. Whilst the existing gold standard for BP measurement is the brachial cuff-based sphygmomanometer, its usage requires a subject to be at rest or motionless when a measurement is taken. The limitations of cuff-based sphygmomanometers have led to clinicians to seek alternative BP measurement tools such as an arterial tonometer, where a pressure transducer exerts a pressure on the radial artery and measures a pressure differential. Both the sphygmomanometer and tonometer require skilled and precise application and cause irritation and discomfort during prolonged usage whilst remaining inconvenientor impractical for the measurement of active subjects.

Technology Features & Specifications

The features and specifications are as follow: Measurement modality: Multiple Photoplethysmograph sensors Parameters: Beat-to-Beat heartrate (HR) Heart-Rate Variability (HRV) Blood Pressure Estimation (BP) Skin temperature Respiration rate (Breaths/min) Arterial Distensibility Sampling Frequency: 2kHz / channel Connectivity options: Bluetooth 5.0, Wi-Fi, USB 3.0 Location: Worn at the wrist (radial artery site)

Potential Applications

In this technology, atool is developed to measure blood pressurecontinuously, comfortably and reliably by measuring pulse wave velocity (PWV) across the forearm at the wrist.PWV has been found to correlate to arterial stiffness and can be used as a surrogate marker for blood pressure. The BP estimation model is derived from PWV measurements utilizing only optical PPG sensors placed on multiple sequential arterial sites on the forearm.

Customer Benefits

This method potentially allows blood pressure to be continuously measured and the data to be wirelessly transmitted to a caregiver for diagnosis. Long-term monitoring will allow more accurate predictive analytics to be obtained and thus profile more accurate machine-learning algorithms to be developed. With continuous-monitoring, other health metrics such as respiration, anomalous cardiac events such as arrhythmia or decreased cardiac output can be determined, with alerts to theseevents generated, allowing for preventive measurements to be taken. As the system sensors are completely optical, it is unaffected by electromagnetic interference (EMI), or by users with pacemakers and will not interfere with ECG or Holter monitoring devices, thus suitable for use in any existing healthcare environment.

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