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Novel Cryogenic Vials for Maximising Storage Space in Cryotanks and Freezers

Technology Overview

Biorepositories or biobanks use vials / containers to store biospecimens at very low temperature for cryopreservation. Existing cryovials used for storage of small solid specimens (about 1 cm3 or smaller) are bulky and are not space-efficient as the cryovialsare designed for liquid specimens. This invention effectively increases the storage space without the need for equipment orinfrastructural upgrade that usually require concomitant changes in labware. The dimensions ofour novel cryovial are compatible to the other commercially-available cryovials for liquid specimenstorage. The novel cryogenic vial is a series of stacked cryogenic vials that nest on top of one anotherthrough the ribbed bottom of the vial into the top of another vial cap. This stacking optimizesthe quantity of specimen stored and prevents recontamination with a threaded cap for everyvial. The effect is a net reduction of storage cost.

Technology Features & Specifications

The novel cryogenic vial is a series of stacked cryogenic vial that nest on top of one anotherthrough the top of another vial cap that fits into the common specimen container tray. The dimensions of the design allow the vials to retrofit into most specimen trays (for 1.5 -2mL) available in the market. This method optimizes the quantity of specimen stored andprevents recontamination with a threaded cap for every vial. Each vial subunit has a cap which engages the body of the vial subunit via external threading. The base of each vial bodyengages the top of a cap via a snap-fit mechanism, where the hinge portion may exist ateither the top of the cap or the base of the vial body. Each cap has an internal annular flange which abuts the top flange of each vial body which defines the opening to the innercompartment of each vial subunit. The cap is made from a softer material than the vial bodyto dispense with the use of an O-ring, which is commonly located between the edge of thecap and the outer flange of a vial body when the cap is screwed on.

Potential Applications

This technology will be applicable in the following areas: • Biobanks - Global biobanking markets are growing due to the prevalence of chronicdiseases and with the forecast for cancer expected to double by 2030, the potential forgrowth is tremendous as the study of cancer involves the storing of solid tumours. • Facilities such as hospital, research laboratories, academic centers, pharmaceuticalsand commercial laboratories

Customer Benefits

These new novel cryovials are compatible with the existing vials used to allow for easyadoption of the technology in all biobanks. Biobanks would not need to change or upgradetheir storage system (such as racks and boxes) when adopting these new vials. Most of all,users will benefit from greater storage efficiency which translates to less storage and freezerspace required, and greater cost savings from space rental and utility fees.

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