Many of us love the warmth and light of the sun; however, often sun exposure causes damages to our skin, according to experienced dermatologists. When our skin is exposed to sunlight, which is the primary source of ultraviolet (UV) radiation in our daily life, our skin gets darkened and damaged, or created by various aesthetic problems, such as wrinkles, blemishes, scarring, freckles and chloasmata, due to the generation of oxidative stress (i.e. free radicals and reactive oxygen species) in the epidermal and dermal layers. Occasionally, the UV-induced damages may even affect certain genes that control the growth and division of our skin cells, leading to the development of melanoma. The technology offers skin whitening function with a specific class of natural compounds which contain in a well-known Chinese medicine providing prominent impact on improving skin condition in the in vitro and in vivo experiments. As these natural compounds are able to reduce melanin formation, they should be decent depigmentation compounds against skin darkening in addition to their antioxidant competence. Herein, these natural agents are the pertinent ingredients for the formulation of skin-whitening and skin-protecting cosmeceuticals.
As the present invention is able to reduce melanin formation, this should be decent depigmentation compounds against skin darkening in addition to their antioxidant competence. Herein, the compounds are the pertinent ingredients for the formulation of skin-whitening and skin-protecting cosmeceuticals. This invention is proved that it can: • attenuate the generation of reactive oxygen species (ROS) and oxidative free radicals; reduce cellular melanin content in melanocytes; and • inhibit the activity of pigment-producing enzymes, namely tyrosinase, TRP-1 and TRP2
The invention is a skin-protection composition that comprises stilbenoid(s) and/or stilbenoid-containing extract(s) obtained from Dendrobium plants, such as Dendrobium officinale and Dendrobium nobile for the management of melanogenesis, skin-darkening and skin-aging. The invention also introduces the usage of Dendrobium ingredients and stilbenoids to reduce the formation of melanin in melanocytes. It also relates to the usage of Dendrobium ingredients and stilbenoids to reduce the generation of reactive oxygen species and oxidative free radicals. This invention relates to the use of Dendrobium-derived extracts or ingredients or stilbenoids as skin-protection, skin-whitening and anti-skin aging products.
• Non-irritatableto skin and non-toxic