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Wireless Photodynamic Therapy Device

Technology Overview

It is a light-emitting device that can be implanted near a tumour through a small incision, by needle-injection, or during surgery and powered wirelessly by a radio-frequency field. The light delivered by the device activates light-sensitive drugs (photodynamic therapy), destroying malignant cells with minimal side effects outside of the treatment region. 

Technology Features & Specifications

It is a miniaturized (30 mg, 15 mm3) implantable photonic device and wireless powering system with the following key advances:

1. deep operation near organs at human size scales

2. multiwavelength light emission at radiant power levels optimized for photosensitizer activation

3. wireless control of light emission for therapeutic dosimetry.

It enables illumination of volumes up to 130 mm3 (assuming a hemisphere volume of radius 4 mm), which is about 8 times the volume of the device.

Potential Applications

Tested for hepatocellular carcinoma and gliobastoma

Potentially also for: other cancers, wet-aged related macular degeneration, psoriasis and atherosclerosis.

 

Market Trends and Opportunities

Primary market: Oncology market

  • $109 billion by 2020
  • Segmented into drugs, surgery, chemotherapy, radiation therapy, targeted therapy, immunotherapy, hormonal therapy, hyperthermia, stem cell transplant and other therapies

 

Specific market: Photodynamic therapy market

  • Valued at USD 2,031.3 Million in 2016.
  • Estimated to reach USD 3,095.9 Million in 2022, growing at a compound annual growth rate of 7.30% between 2016 and 2022

Customer Benefits

  1. Non-mutagenic (can be performed multiple times without fear of introducing oncogenic DNA mutations)
  2. Non-scarring
  3. High selectivity to cancer tissue
  4. Can deliver multiple doses of light to suppress tumour growth.
  5. Can activate photosensitizers through thick tissues (>3 cm).

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