Discover new technologies by our partners

Conventional tissue processing techniques rely heavily on chemical and biological agents. These agents affect the inherent structural and mechanical properties of the grafts. Our proprietary platform using supercritical carbon dioxide (scCO2) provides a mild and efficient platform to clean tissue with limited use of chemicals. Research has shown that the use of scCO2 minimally affects the structural integrity of tissue grafts when compared to conventional processing techniques. scCO2 treatment also removes medullary tissues responsible for adverse immune response. In addition to the scCO2 treatment step, the platform includes a viral inactivation step. The combination of these two techniques has been shown to achieve a 12-fold reduction in the microbial load in the processed grafts. The successful removal of cellular and medullary materials and inactivation of viruses is the most crucial step in ensuring cleaner grafts for better patient outcomes. By using scCO2 as the cleaning solvent, excessive incubation in detergents becomes unnecessary, thus reducing the risk of residuals of processing and extra-cellular matrix denaturation.

The majority of the local indoor farmers grow crops that are harvested for their leaves. One way to increase the growth rate of such leafy greens is to provide a longer period of light. However, some of the crops grown, e.g., spinach, are long-day plants that flower when the light periods are longer than their critical day-length. While important to a plant’s life cycle, this vegetative to reproductive phase change is undesirable for farmers, not only because it shortens the harvest period hence reducing the yield, but also because it changes the taste profile. To tackle this problem, a light recipe that was able to suppress flowering was formulated. Plants grown under this light recipe showed a faster growth rate than those grown under flowering-suppressing short-day photoperiod. Moreover, they do not flower even when the light period has surpassed the critical day-length. Positive results were obtained when this light recipe was tested on spinach and arugula. This technology would work for other long-day crops, and it will be beneficial to indoor farmers who are interested to try it.

Rheumatoid arthritis (RA) is a chronic, autoimmune disease that most commonly afflicts joints in the hands, wrists and knees. It arises when the immune system mistakenly targets the body’s own tissues, triggering inflammation that could lead to irreversible damage in the long run. Patients with RA often complain of swelling, pain and stiffness of the joints. In the most severe cases, RA can cause limb deformity and, ultimately, loss of function. There is no single test that can conclusively diagnose RA, and doctors typically have to run several to make sure. One such test is the X-ray, which helps visualise which joints are inflamed and to what degree. There are several methods for scoring X-ray radiographs, but most of them are manually graded, so physicians still need to attend to each image individually. As a result, interpretation of X-rays tends to be subjective and, depending on how well-staffed a hospital is, can take up to several days. RA is the most common type of autoimmune arthritis. In Singapore, around one percent of the population have RA, equivalent to tens of thousands of radiographs requiring interpretation. There is therefore a need for an automated approach of processing these X-ray images quickly without sacrificing diagnostic quality. The described invention is a deep learning algorithm that automatically scores X-ray radiographs and accurately assesses the severity of joint damage.

The most common cryopreservation media used in laboratories consist of 10% DMSO and 20% to 90% fetal bovine serum (FBS). DMSO was thought to reduce the size of ice-crystals during freezing, thus reducing mortality whereas FBS improves the viability of cells during recovery.  Although effective for cryopreservation of most cell types, FBS poised significant risks, including the possible risk of cross-species virus infections such as the “mad cow disease”, as well as the possibility of triggering an adverse immunogenic response from the recipient. Our serum-free cryopreservation formula allows the cryopreservation of mammalian cells without the need for serum.

We are an AI-based intelligent video analytics provider, our platform extracts detailed information from the existing CCTV based infrastructure and provides rich insights that are capable of transforming images and videos into meaningful granular data that can be leveraged for automated surveillance solutions, in-depth analysis, and business intelligence reporting: People analytics: including deep face recognition (with mask and without mask), clothing attributes, social distance violations, activities including violence, crowding, etc. Traffic analytics: including vehicle make/model, speeding, automatic number-plate recognition (ANPR), various driving and parking violations. Workplace safety analytics: including personal protective equipment (PPE) compliance, hazards, abandoned objects, intrusions. Retail analytics: including shopper behavioral, product interaction analytics, shopper experience, and shoplifting vulnerability.

Polymeric dielectrics are principal materials for high power density electric energy storage applications. They exhibit superior processability, high dielectric breakdown strength and exceptional self-healing properties. Among this group of dielectrics, polyvinylidene fluoride (PVDF) is the most promising for energy storage applications due to its ferroelectric nature. However, the ability to produce a polar phase with relaxor-like behaviour and high energy storage density in PVDF is a major challenge, thus limiting its practical applications. Currently, this has only been achieved using complex and expensive synthesis of PVDF copolymers and terpolymers or via irradiation with high-energy electron-beam or γ-ray radiations. The technology on offer provides a proprietary method of producing ferroelectric β-PVDF with relaxor-like behaviour without the need of any hazardous gases, solvents, electrical or chemical treatments. This simple and scalable processing route generates unprecedentedly high β-phase content (approx. 98 wt. % of crystalline phases) and is generally applicable to PVDF of different molecular weights (Mw). Relaxor-like ferroelectricity is achieved in PVDF with high Mw (at least 534 kg/mol). An ultra-high energy density of 29 J/cm3 can be achieved at 800 kV/mm in PVDF (Mw: 670-700 kg/mol) produced by this method, which is one of the highest values ever reported for a polymer based dielectric capacitor.

We have developed a range of customizable cosmetic formulations that are non-greasy and non-tacky and can be readily adapted to suit the specific needs of an identified target market; such as for the Asian consumers.  The developed base fomulation also enable flexibility for actives to be incorporated to deliver specific claims for a personal care and/or cosmetic product.  Its non-greasy and non-tacky formulations are important for Asian countries where humidity levels can be high and affect consumer acceptance of a cosmetic product. Industry will now have a platform they can have access to, enabling translation of ideas into commercial products at a much faster pace; whereas in the past, such research has to start from scratch or the companies need to purchase off the shelf formulations sold by ingredient providers.  With these ready-made formulations customised to the local market needs, companies can now have access to a formulation they own and allow for smaller tweaks for further personalisation efforts. Customisation to Asian context to ensure success rate is important. One of the key customisation for the formulations developed in this effort includes improved sensory evaluation of cosmetics.  

A sustainable mechanical-based processing line that works with a variety of plant ingredients to produce solvent-free and chemical-free oils and fats together with high protein and fibre powder. The protein and fibre content depends on the type of plant used. This processing method is currently on pilot scale of 1 tonne per hour approximately and can be scaled much higher for mass industrial requirements. The company is seeking for partners to scale up their processing method and/or strategic partners to enter into a joint venture.

To advance intelligent satellites, a new Latchup-Detection-And-Protection (LDAP) Integrated Circuit (IC) is offered to enable the application of Commercially-Off-The-Shelf (COTS) ICs in satellites for the first time. State-of-the-art COTS ICs can latch up (Single Event Latchup) when a heavy particle strikes, resulting in permanent damage.  The new LDAP offers a novel unprecedented means to protect state-of-the-art COTS. The technology solution is supported by a full set of Radiation-Hardened-By-Design (RHBD) digital library cells whose attributes include ultra-low error-rate and yet low area-, power-, and delay-overheads when compared to the state-of-the-art solutions.  The RHBD library cells are space-grade, not only increasing the lifespan of the electronics in space environments, but also enabling unprecedented higher processing power (more intelligence) for electronics.